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Skin Doctors Relaxaderm reduces the visible appearance of wrinkles by up to 50% in 30 just days. With incredible skin relaxing properties, Relaxaderm can delay the appearance of premature ageing so you can enjoy smoother, younger looking skin. How to Use: After cleansing, gently massage evenly over face and neck. Follow with daily or nightly moisturiser. For best results use twice daily, morning and evening. Active Ingredients: Acetyl Hexapeptide-8: a chain of 6 amino acids which works by inhibiting the release of neurotransmitters that are responsible for the contraction of facial muscles. As a result, Argireline relaxes facial tension leading to the minimisation of facial lines and wrinkles, giving the whole face a relaxed, more youthful look. Tests have shown that the Argireline reduces the appearance of wrinkles by up to 50% in 30 days, with an average improvement of 30%. This resembles the effect of Botox®, which reduces facial tension and movement by paralysing facial muscles.